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NIS expression confers iodide and astatide uptake ability. Uptake of iodide and astatide in UVW cells transfected with cDNA for either the human NIS (NIS 6) or lac-Z (UVW-lac-Z). Results are means ± standard deviation (n = 3). Reprinted from: Carlin et al. Sodium-iodide symporter (NIS)-mediated accumulation of [211At]astatide in NIS-transfected human cancer cells. Nucl. Med. Biol. 2002, 29, 729-739 with permission from Elsevier Ltd.
