Table 1. mRNAs altered in response to activin A.

A selection of candidate activin-regulated genes identified by Affymetrix microarray in immature (6 dpp) and post-mitotic (15 dpp) murine Sertoli cells, expressed as fold change relative to untreated cells. Putative biological functions are indicated. ND = not detected.

mRNAs upregulated in response to activin A (fold change relative to untreated cells)
Accession number	Symbol	Function	6 dpp		15 dpp
			5 ng/ml	50 ng/ml	5 ng/ ml
BF322785	Mup1	chemical signalling	4.2	2.3	ND
NM_010475	Hsd17b1	steroidogenesis	2	4.3	ND
NM_008291	Hsd17b3	steroidogenesis	1.85	2.3	ND
BE446879	Rbm5	RNA binding	1.8	0.8	0.9
NM_011980	Zfp14	zinc finger protein	2.4	1.1	1.3
NM_007706	Socs2	suppressor of cytokine signalling	1.4	2.6	1.2
NM_010950	Numb-like	Numb is an inhibitor of notch signalling	0	0.8	2
NM_008785	Serpina5	serine protease inhibitor, male fertility	1.4	2.5	1.7
NM_021344	Tescalcin	Ca2+ binding protein	1.6	2.6	1.1
NM_031380	Fstl3	repressor of activin signalling	1.2	2.2	1
BC023427	Pdgfb	growth factor	1.4	2	1
AV343573	Cbln4	member of TNFα superfamily	1.5	2	ND
AF249668	Rnf14	ring finger protein	ND	2.4	2.4
BC013493	Slc13a2	solute carrier	ND	9	0.8
AK019971	Prrx2	homeobox protein	1.5	2.2	ND
mRNAs downregulated in response to activin A (fold change relative to untreated cells)
Accession number	Symbol	Function	6 dpp		15 dpp
			5 ng/ml	50 ng/ml	5 ng/ ml
NM_007522	Bad	pro-apoptotic	0.4	0.7	0
BB035017	Rarres1	tumour suppressor	0.7	0.4	0.8
NM_007825	Cyp7b1	cytochrome P450 family	0.8	0.5	ND
AF300870	Csen	calsenilin binding protein	0.6	0.2	ND
BC026153	Epha7	Eph receptor a7	0.7	0.4	ND
AI451018	Plxnb3	axon guidance receptor	0.5	0.6	ND