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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Heart Rhythm. 2009 Oct 12;7(2):199–205. doi: 10.1016/j.hrthm.2009.10.012

Figure 4.

Figure 4

Two KCNE2 transmembrane variants, I57T and M54T, increase the reconstituted Kv4.3 + KChIP2b channel current and slow its inactivation. A: Three sets of current traces elicited by depolarizing pulses for 500 ms from a holding potential of −80 mV to potentials ranging between −40 and +50 mV in 10-mV increments (same protocol as in experiments of Figure 1A). B: Superimposition of three original current traces recorded upon depolarization showing variant-related increase in peak outward current density. C: Current–voltage relationship curve showing average peak outward current densities (*P <.05 vs Kv4.3 + KChIP2b + WT). WT = wild type.