Table 1.

Response rates following isolated limb perfusion with melphalan in patients with melanoma.

Study	Patients (n)	Conditions	CR (%)	PR (%)	Ref.
Minor (1985)	18	Hyperthermia	82	18	[15]
Storm (1985)	26	Hyperthermia	50	31	[16]
Kroon (1987)	18	Normothermia	38	44	[17]
Di Filippo (1989)	69	Hyperthermia	39	43	[18]
Kroon (1993)	43	Normothermia	77	14	[19]
Klasse (1994)	120	Normothermia	54	25	[20]
Aloia (2005)	59	Hyperthermia	57	31	[21]
Cornett* (2006)	58	Hyperthermia	25	39	[22]
Sanki (2007)	120	Hyperthermia	69	15	[14]

^*Randomized, controlled trial.

CR: Complete response; ILP: Isolated limb perfusion; PR: Partial response.