Skip to main content
. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Clin Lipidol. 2009 Dec;4(6):767. doi: 10.2217/clp.09.57

Figure 1. CD36 has two transmembrane domains (yellow), two short cytoplasmic domains and a large extracellular domain.

Figure 1

The latter contains three disulfide bonds clustered near the N-terminal transmembrane domain and independent binding sites for TSR-containing proteins (blue) and oxLDL (red) on the N-terminal half. The C-terminal cytoplasmic domains directs intracellular signaling via activation of specific Src-family and MAP kinases. TSR: Thrombospondin type I repeat.