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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Contemp Clin Trials. 2009 Sep 27;31(1):44. doi: 10.1016/j.cct.2009.09.007

Table 2.

Recruitment methods and reasons for study withdrawal.

Author Study intervention Recruitment methods Reasons for withdrawal
Carbonell et al.
(2008)13
Mifepristone 5mg
vs. 10 mg
Study/clinic personnel Adverse event
Hehenkamp et al.
(2008)14
UAE* vs.
hysterectomy
Study/clinic personnel, local
newspaper
Patient preferred treatment,
declined allocated
treatment
Levens et al.
(2008)15
CDB-2914 vs.
placebo
Study/clinic personnel,
media sources, internet
postings, community
outreach
Declined allocated
treatment, pelvic pain,
failure to follow-up
Mara et al.
(2008)16
UAE* vs.
myomectomy
Study/clinic personnel Patient refused enrollment,
exclusion criteria, failure to
follow-up
Wilkens et al.
(2008)17
Asoprisnil vs.
placebo
Study/clinic personnel Exclusion criteria
Chwalisz et al
(2007)18
Asoprisnil vs.
placebo
** Adverse event, protocol
violation, withdrawal of
consent, failure to follow-
up
Hald et al.
(2007)19
Laparoscopic
occlusion vs. UAE*
Study/clinic personnel Patient preferred treatment,
declined allocated
treatment, failure to follow-
up
Muneyyirci et al.
(2007)20
Pre-op Goserelin
vs. Iron
monotherapy
** Adverse reaction to
medication, subject non-
compliance, withdrawal of
consent, failure to follow-
up
Fiscella et al.
(2006)21
Mifepristone vs.
placebo
Study/clinic personnel, local
media, community physician
referrals
Patient declined following
randomization
Mara et al.
(2006)22
UAE* vs.
myomectomy
Study/clinic personnel Patients declined
enrollment
Donnez et al
(2003)23
Fulvestrant vs.
goserelin
Study/clinic personnel Protocol deviation, adverse
event
Palomba et al.
(2002)24
Leuprolide plus
raloxifene vs.
leuprolide plus
placebo
Study/clinic personnel Patient non-compliance,
failure to follow-up
Verspyck et al.
(2000)25
Leuprorelin vs.
lynestrenol
** Adverse event, failure to
follow-up, protocol
deviation
*

UAE: uterine artery embolization

**

Information not provided