Table 1.
Baseline lipid class concentrations (nmol/g) in the heart and plasma of PD2 and PD60 rats - effects of age.
| Lipid Class | Source | PD2 | PD60 | P Value |
|---|---|---|---|---|
| Cholesterol Ester (CE) | Heart | 337.75 ± 96.09 | 424.50 ± 102.75 | 0.560 |
| Plasma | 1249.00 ± 41.23 | 1449.00 ± 48.61* | 0.020 | |
| Diacylglycerol (DAG) | Heart | 293.75 ± 30.56 | 334.00 ± 13.10 | 0.272 |
| Plasma | 65.75 ± 8.84 | 30.00 ± 7.22* | 0.020 | |
| Free Fatty Acid (FFA) | Heart | 1230.00 ± 113.48 | 2093.50 ± 153.14* | 0.004 |
| Plasma | 689.25 ± 53.22 | 653.00 ± 27.42 | 0.567 | |
| Lysophosphatidylcholine (LPC) | Heart | 423.75 ± 35.01 | 487.00 ± 36.79 | 0.259 |
| Plasma | 394.25 ± 13.92 | 393.00 ± 34.47 | 0.974 | |
| Phosphatidylcholine (PC) | Heart | 8091.75 ± 759.67 | 14169.25 ± 789.30* | 0.001 |
| Plasma | 1246.25 ± 35.92 | 1130.50 ± 21.52* | 0.033 | |
| Phosphatidylethanolamine (PE) | Heart | 6896.00 ± 624.50 | 12343.00 ± 434.87* | <0.001 |
| Plasma | 324.00 ± 23.01 | 181.75 ± 24.55* | 0.006 | |
| Phosphatidylserine (PS) | Heart | 1321.33 ± 159.17 | 1614.75 ± 62.90 | 0.112 |
| Plasma | n/a | n/a | ||
| Triacylglycerol (TAG) | Heart | 1038.00 ± 147.45 | 999.25 ± 360.61 | 0.924 |
| Plasma | 1527.50 ± 108.83 | 331.50 ± 39.01* | <0.001 | |
| Free Cholesterol (FC) | Heart | 3762.25 ± 327.30 | 3651.00 ± 151.38 | 0.768 |
| Plasma | 632.75 ± 30.51 | 622.25 ± 22.22 | 0.790 |
Data are presented as mean ± SEM. * Significantly different from PD2 rats. N = 4 samples for each experimental group. Note: plasma from 2-3 pups was pooled to generate one sample. N/A = not applicable.