Table 3.
Plasma lipid profiling in PD2 and PD60 rats - effects of hypoxia and recovery.
| Lipid Class - Fatty Acid | Baseline | 2 h of Hypoxia | 2 h Recovery From Hypoxia |
|---|---|---|---|
| PD2 Plasma | |||
| FFA - 16:0 | 173.62 ± 15.61 | 90.62 ± 5.42e | 146.32 ± 7.90 |
| FFA - 18:1n9 | 80.02 ± 10.08 | 37.60 ± 2.89d | 66.52 ± 3.73 |
| FFA - 18:2n6 | 104.57 ± 6.31 | 47.90 ± 5.80e | 91.22 ± 3.16 |
| FFA (total) | 689.25 ± 53.22 | 344.50 ± 26.29e | 614.75 ± 27.21 |
| PD60 Plasma | |||
| FFA - 16:0 | 192.52 ± 10.04 | 350.65 ± 12.19e | 160.42 ± 14.72 |
| FFA - 16:1n7 | 19.45 ± 1.24 | 50.07 ± 2.90e | 17.00 ± 2.24 |
| FFA - 18:1n9 | 101.42 ± 5.50 | 211.85 ± 3.29e | 82.70 ± 8.92 |
| FFA - 18:2n6 | 167.85 ± 3.99 | 363.10 ± 11.27e | 134.65 ± 18.16 |
| FFA (total) | 653.00 ± 27.42 | 1249.00 ± 46.82e | 538.00 ± 53.79 |
| TAG - 20:4n6 | 76.10 ± 8.94 | 177.45 ± 24.25d | 128.22 ± 9.35a |
| LPC - 20:4n6 | 54.57 ± 5.55 | 36.55 ± 5.81a | 34.35 ± 1.46a |
Animals were exposed to hypoxia (8% O2) for 2 h or exposed to hypoxia for 2 h and allowed to recover in room air (21% O2) for an additional 2 h. Due to the size of the data set produced by the lipid profiling analyses, only significant changes (p < 0.05) are shown. Data are presented as mean ± SEM (nmol/g plasma). All comparisons were made versus Baseline as follows: a P < 0.05, b P < 0.02, c P < 0.01, d P < 0.005, and e P < 0.001. N = 4 samples for each experimental group. Note: plasma from 2-3 PD2 rats was pooled to generate one sample. Lipid class abbreviations can be found in the legend of Table 1.