Table 1.

Comparison of control and hypertensive mice.

	control	DOCA	p value
	(n=10)	(n=9)
Systolic	98 ± 5	114 ± 2	0.01
HR (beats/min)	564 ± 15	609 ± 14	0.03
Diastolic	(n=4)	(n=6)
E’ (cm/s)	5.6 ± 0.2	2.9 ± 0.2	<0.001
E’/A’	1.5 ± 0.1	0.7 ± 0.1	<0.001
Vp (cm/s)	50.8 ± 1.9	29.8 ± 1.4	<0.001
E/E’	16.1 ± 0.8	29.0 ± 1.5	<0.001
E/A	1.4 ± 0.4	1.5 ± 0.1	NS
Systolic
	(n=6)	(n=5)
%FS (%)	29 ± 1.9	33 ± 2.0	NS
%EF (%)	56 ± 2.9	60 ± 0.2	NS
Sm (cm/s)	3.3 ± 0.4	2.9 ± 0.1	NS
LV dimensions
	(n=6)	(n=5)
LVPWd (mm)	0.74 ± 0.01	0.76 ± 0.01	NS
LVEDd (mm)	3.8 ± 0.1	3.7 ± 0.2	NS
Myocyte
	(n=9)	(n=9)
Diameter (µm)	16.9 ± 0.5	16.8 ± 0.3	NS
	(n=6)	(n=6)
Length (µm)	123.2 ± 6.1	111.3 ± 12.9	NS

BP, blood pressure; HR, heart rate; E’, early septal mitral annulus velocity measured by tissue Doppler imaging (TDI); A’, late diastolic septal mitral annulus velocity (TDI);Sm, systolic septal mitral annulus velocity (TDI); Vp, left ventricular inflow propagation velocity by color M-mode Doppler; E, early diastolic filling velocity measured by conventional Doppler; A, late diastolic filling velocity measured by conventional Doppler; %FS, percent fractional shortening; %LVEF, percent ejection fraction; LV, left ventricle; LVPWd, LV posterior wall thickness; LVEDd, LV end diastolic dimension.