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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2010 Feb;34(2):178. doi: 10.1097/PAS.0b013e3181cc7e79

Figure 4. PD-1 patterns in PTGC and NLPHL.

Figure 4

(A) PTGC – note the prominent nodule with disrupted germinal center adjacent to reactive follicles (H&E, 100x). (B) PD-1 staining is increased within the PTGC nodules (100X). (C) PD-1 staining is also increased in the paracortical zones surrounding the PTGC nodules (200x). (D) PD-1-positive GC-T-cell rosettes are clearly highlighted in a case previously diagnosed as florid PTGC but was found to have focal involvement by NLPHL (400X).