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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Dev Cell. 2009 Oct;17(4):494. doi: 10.1016/j.devcel.2009.08.008

Figure 4. Seam Cell Positioning Defects in lat-1 Mutants.

Figure 4

(A and A′) The seam cell marker RNT-1::GFP labels two seam cell rows of ten cells each on either side of WT embryos.

(B and B′) RNT-1-positive cells persist on the right side in lat-1 mutant.

(C and D) The migration path of H2 seam cells and their precursors was traced by 4D microscopy. Green, migration path of common ABarpp precursors. Movement of ABarpp descendants after left-right split of cell lineage: blue, left descendants (ABarppax); yellow, right descendants (ABarpppx); spheres, final destination of differentiated seam cells. (C) Contralateral migration of H2L/H2R in WT embryo. (D) In a lat-1 embryo left-right migration is absent, and H2L and H2R stay together. Dorsal views, anterior to the left. Scale bar = 5 μm.