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. Author manuscript; available in PMC: 2010 Feb 10.
Published in final edited form as: J Biol Chem. 2007 Mar 27;282(20):14807. doi: 10.1074/jbc.M611550200

FIGURE 1. Pathway of de novo glycerolipid synthesis.

FIGURE 1

GPAT isoforms located in mitochondria (GPAT1) and endoplasmic reticulum (ER) (GPAT3) catalyze the initial step in the synthesis of TAG. Acyl-CoA use for β-oxidation or TAG synthesis is regulated reciprocally by carnitine palmitoyltransferase-1 (CPT-1) and GPAT1. LPA, phosphatidic acid (PA), and DAG, TAG, phosphatidylethanolamine (PE), phosphatidylcholine (PC), and fatty acid (FA) were used.