FIGURE 3. Liver, skeletal muscle, and VLDL TAG content was increased in Ad-GPAT1-treated rats.
Rats were treated with 1.0–2.0 × 1012 particles/ml of Ad-GPAT1 or Ad-EGFP virus for 5–7 days and fasted for 4 h before tissue collection. Ad-EGFP, n = 9. and Ad-GPAT1, n = 11, for liver and gastrocnemius. Results are expressed as mean ± S.E. A, liver TAG. B, gastrocnemius muscle TAG. Plasma lipoprotein fractions were separated by fast protein liquid chromatography. Triglyceride and cholesterol are reported as averages (EGFP, n = 4; GPAT, n = 6). C, VLDL TAG (fraction 14; * p < 0.05). D, VLDL cholesterol (fraction 14; p < 0.06).