. Author manuscript; available in PMC: 2010 Aug 1.

Published in final edited form as: Nat Med. 2010 Jan 17;16(2):232. doi: 10.1038/nm.2080

Table 2.

SRC Frequency Determined by Limiting Dilution Analysis

	3 weeks post transplant			9 weeks post transplant

No. of CD34+ starting cells per mouse	No. of mice engrafted with ≥ 0.5 % CD45/total no. of mice			No. of mice engrafted with ≥ 0.5 % CD45/total no. of mice
	Delta 1	Control	Non-cultured	Delta 1	Control	Non-cultured
1200	3/46	0/38		5/45	1/36
6000	24/46	7/36	2/41	15/45	7/36	3/36
30000	46/46	23/32	6/44	43/43	27/30	17/42
150000			32/42			34/38
No. of SRC/10⁶ starting cells	125	38^***	8^***	99	56^*	16^***

p=0.01,

^***

p=0.0001; reference group Delta1^ext-IgG, 3 and 9 weeks