Table 4.

Association of MPDZ Haplotypes With AlcoholismWithout AWS

	SNP
Haplotype	−436 Upstream*	rs13297480*	rs2274856*	rs1331674	rs3831219*	rs1331672	rs10756457*	rs7024892	rs2297003	rs2274647*	rs3765550*	rs3264*	rs722651*	Haplotype frequency	Simulated p-value	Max statistic simulated p-value
1		A	G	G		C	A	A	G	A	A	G	C	0.0621	0.087
2		A	G	G		C	A	A	G	A	A	A	C	0.0725	0.164
3		A	G	G		C	A	A	G	A	G	A	T	0.2421	0.162
4	insT	A	A	A	delCTC	G	G	G	A	C	A	A	C	0.0520	0.916
5	insT	A	G	G		C	A	A	G	C	A	A	C	0.0980	0.179
6		A	G	G		C	A	A	G	A	G	G	C	0.0774	0.063
7		G	A	A	delCTC	G	G	G	A	A	A	G	C	0.0746	0.006	0.051

AWS, alcohol withdrawal seizure.

Global score test statistic = 16.90, df = 7, Global simulation p-value = 0.015.

^*Tag-SNP.

p values below 0.05 are presented in bold.