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Responses of a single DA neuron evoked with mPFC stimulation before and after application of orexin A to the recorded neuron. Left panel shows the responses of a DA neuron evoked with 1 mA stimulation of the mPFC. Right panel shows the responses of the same neuron to the same stimulation approximately 5 min following delivery of 60 nl of 1.4 µM orexin A locally onto the recorded neuron. Dashed line is the onset of stimulation. Taken from (Aston-Jones et al., 2009).
