Table 1.

Half-time of aging for human acetylcholinesterase and human butyrylcholinesterase inhibited by organophosphorus compounds

Human AChE
OP	R1	R2	t (°C)	pH	t1/2	Reference
soman *	(CH3)3C(CH3)CHO	CH3	27	8.0	6.3 min	[61]
sarin	(CH3)2CHO	CH3	37	8.0	3.9 h	[62]
cyclosarin	cyclohexyl-O	CH3	37	7.4	8.7 h	[63]
tabun	(CH3)2N	CH3CH2O	37	7.4	13.6 h	[64]
DFP	(CH3)2CHO	(CH3)2CHO	37	7.8	4.4 h	[65]
paraoxon-ethyl	CH3CH2O	CH3CH2O	37		41 h	[63]
paraoxon-methyl	CH3O	CH3O	37	7.4	3.7 h	[66]
Human BChE
OP	R1	R2	t (°C)	pH	t1/2
soman*	(CH3)3C(CH3)CHO	CH3	25	8.0	9 min	[67]
sarin	(CH3)2CHO	CH3	37	7.4	5.8–6.4 h	[64]
cyclosarin	cyclohexyl-O	CH3	37	7.4	2.2 h	[63]
tabun	(CH3)2N	CH3CH2O	37	7.4	6.1–6.4 h	[64]
DFP	(CH3)2CHO	(CH3)2CHO	37	7.8	28 min	[65]
paraoxon-ethyl	CH3CH2O	CH3CH2O	20	8	11.6 h	[63]
paraoxon-methyl	CH3O	CH3O	37	7.4	3.9 h	[66]

^*racemic soman