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. Author manuscript; available in PMC: 2011 Feb 16.
Published in final edited form as: Brain Res. 2009 Nov 12;1314C:235. doi: 10.1016/j.brainres.2009.11.015

Figure 3. The structure of the OPRM1 gene and location of the polymorphisms.

Figure 3

A- Exon-intron structure of the OPRM1 gene reported in Wendel and Hoehe (1998). The position of the ATG initiation codon is indicated. The numbering of the polymorphism position is based upon a system that gives value +1 to the first nucleotide of this codon; bases belonging to the coding region have positive values; bases belonging to the upstream 5’ to the initiation codon have negative values. The protein coding region is indicated in black.

B- The structure of OPRM1 mRNA. The protein coding region is indicated in black.

C- The seven transmembrane domain structure of the OPRM1 protein. Transmembrane domains (TM1-TM7) are indicated in rectangles.