A- The structure of the POMC gene with selected polymorphisms. The position of the ATG initiation codon is indicated. The numbering of the polymorphism position is based upon a system that gives value +1 to the first nucleotide of this codon. The protein coding region is indicated in black.
B- The structure of POMC mRNA. The protein coding region is indicated in black.
C- POMC peptides. Selected functional polymorphisms are indicated.