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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Microbes Infect. 2009 Nov 17;12(2):126. doi: 10.1016/j.micinf.2009.11.003

Fig. 4.

Fig. 4

F. tularensis induces caspase 1 activation in hMDMs. (A) Representative confocal laser scanning microscopy images of hMDMs infected with the wt strain or iglC mutant. The activation of caspase 1 (C1) and apoptosis (TUNEL) were determined at 1, 6 and 24 h post infection. (B) Quantitative analysis of C1 activation in C3 inhibited cells stained for cell death. Approximately 100 macrophages were analysed by confocal microscopy from different coverslips. The data are representative of three independent experiments and error bars represent standard deviations. The asterisks represent statistically significant difference.