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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Microbes Infect. 2009 Nov 17;12(2):126. doi: 10.1016/j.micinf.2009.11.003

Fig. 6.

Fig. 6

Resistance to apoptosis-inducing agents. (A) Representative confocal microscopy images of hMDMs macrophages infected with either F. tularensis subsp. novicida wild type strain or iglC mutant strain. Staurosporin was used to induce artificially apoptosis of the macrophages. The cells were stained with both the TUNEL assay labelling (red) and the active Caspase-3 antibodies (blue). (B) Quantitative analysis of cell death in staurosporin treated cells. Approximately 100 macrophages were analysed by confocal microscopy from different coverslips. The asterisks represent statistically significant difference.