Table 4. Sensitivity analysis of the association between pretransplant restriction and early respiratory failure.
Unadjusted | Adjusted* | |||||
---|---|---|---|---|---|---|
N (%) | Events | HR (95% CI) | p-value | HR (95% CI) | p-value | |
TLC<80% | ||||||
No | 2351 (92) | 261 | - | - | ||
Yes | 194 (8) | 43 | 2.22 (1.60 - 3.07) | <0.001 | 1.90 (1.36 - 2.65) | <0.001 |
TLC<80%+FEV1/FVC >0.7 | ||||||
No | 2358 (93) | 263 | - | - | ||
Yes | 185 (7) | 41 | 2.19 (1.57 - 3.06) | <0.001 | 1.90 (1.35 - 2.66) | <0.001 |
TLC<80%+FEV1/FVC >0.7+low probability on chest imaging | ||||||
No | 2396 (93) | 275 | - | - | ||
Yes | 143 (6) | 28 | 1.84 (1.25 - 2.71) | 0.002 | 1.59 (1.07 - 2.37) | 0.022 |
Adjusted for disease risk and year
TLC=total lung capacity; FEV1=forced expiratory volume in one second; FVC=forced vital capacity; HR=hazard ratio; CI=confidence interval