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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Gastroenterology. 2009 Sep 24;138(2):671. doi: 10.1053/j.gastro.2009.09.021

Figure 6. Inhibition of TNF-α and IFN-γ secretion by Tetanus toxoid and Candida albicans-specific T cells.

Figure 6

Figure 6

Figure 6

Figure 6

Fresh PBMC from two representative HCV-infected subjects (A, C and B, D) were cultured with Tetanus and Candida protein antigens and PHA, with or without MK001 (20 μg/mL) for 4 days. Culture supernatants were frozen at −80°C and subsequently tested by multiplex ELISA for the presence of TNF-α and IFN-γ (sensitivity of detection: 2 pg/mL for both). No cytokine secretion was detected in the absence of protein antigens. Similar results were obtained in 5 HCV-infected and 2 HCV-uninfected subjects.