Table 1. Studies Reporting Stress-ralated Behaviors mediated by the Dynorphin-Kappa Opioid Receptors System.

Stimulus	Behavior	Species	Reference
Stress	Swim-stress immobility	Mouse/Rat	Pliakas et al., 2001; McLauglin et al., 2003; Shiriyama et al., 2004; Mague et al. 2003
	Social Defeat Stress	Mouse	McLaughlin et al., 2006
	Potentiation of Cocaine CPP	Mouse	McLaughlin et al., 2003; McLaughlin et al., 2006
	Stress-induced Reinstatement	Mouse/Rat	Beardsley et al., 2005; Redila and Chavkin, 2008; Carey et al., 2007
		Monkey	Valdez et al., 2007
	Novel Object Recognition	Mouse	Carey et al., 2009
	Stress-induced Avoidance	Mouse	Land et al., 2008
KOR	Conditioned Place Aversion	Mouse/Rat	Bals-Kubik et al. 1993; Land et al., 2008; Contarino and Papeleo et al., 2005; Kim et al., 2004; Shippenberg and Herz 1986; Bruchas et al., 2007
	Potentiation of Cocaine CPP	Mouse	McLaughlin et al., 2003; McLaughlin et al., 2006
	Intracranial Self Stimulation	Rat	Tomasiewicz et al., 2008
	Anxiety-like behavior	Mouse/Rat	Knoll et al., 2007; Wittman et al., 2009
	Reinstatement to Drug Seeking	Mouse/Monkey	Redila and Chavkin, 2008; Valdez et al., 2007
	Locomotor Activity	Rat	Heidbreder et al., 1993
CRF-R	Conditioned Place Aversion	Mouse	Land et al., 2008
	Anxiety-like Behavior	Mouse	Wittman et al., 2009, Beliki-Gorzo et al., 2008