Table 1. American Joint Committee on Cancer (AJCC) Pancreatic Cancer Staging, SEER Historic Staging, and Technical Resectability.
PRIMARY TUMOR (P) | ||
TX: Primary tumor cannot be assessed | ||
T0: No evidence of primary tumor | ||
Tis: Carcinoma in situ | ||
T1: Tumor is limited to the pancreas and is 2 cm or less in greatest dimension | ||
T2: Tumor is limited to the pancreas and is more than 2 cm in greatest dimension | ||
T3: Tumor extends beyond the pancreas without involvement of the celiac axis or superior mesenteric artery | ||
T4: Tumor involves the celiac axis or the superior mesenteric artery (unresectable primary tumor) | ||
REGIONAL LYMPH NODES (N) | ||
NX: Regional lymph nodes cannot be assessed | ||
N0: No regional lymph node metastasis | ||
N1: Regional lymph node metastasis | ||
DISTANT METASTASIS (M) | ||
MX: Distant metastasis cannot be assessed | ||
M0: No distant metastasis | ||
M1: Distant metastasis | ||
AJCC STAGING GROUPS | SEER HISTORIC STAGING | RESECTABILITY |
Stage 0: Tis, N0, M0 | Localized | Resectable |
Stage IA: T1, N0, M0 | Localized | Resectable |
Stage IB: T2, N0, M0 | Localized | Resectable |
Stage IIA: T3, N0, M0 | Regional | Potentially resectable* |
Stage IIB: T1-3, N1, M0 | Regional | Potentially resectable* |
Stage III: T4, any N, M0 | Regional | Unresectable |
Stage IV: Any T, any N, M1 | Distant | Unresectable |
Resectable if no major portal/superior mesenteric venous involvement or major retroperitoneal involvement present (locally advanced disease).