Table 3.
Comparison of 9168 survivors reporting no prior HCV testing versus those reporting a prior test for HCV †
| Univariate Model* | Multivariate Model* | |||||
|---|---|---|---|---|---|---|
| Characteristics | OR | 95% CI | P-value | OR | 95% CI | P-value |
| Diagnosis | ||||||
| Acute lymphoblastic leukemia | 0.7 | 0.6 – 0.8 | <0.001 | 1.0 | 0.8 – 1.2 | 0.715 |
| Acute myeloid leukemia | 0.4 | 0.3 – 0.6 | <0.001 | 0.7 | 0.5 – 1.0 | 0.041 |
| Other leukemias | 0.7 | 0.5 – 1.0 | 0.021 | 1.0 | 0.7 – 1.4 | 0.808 |
| CNS tumor | 1.4 | 1.2 – 1.7 | 0.001 | 1.5 | 1.2 – 1.8 | <0.001 |
| Kidney (Wilms) | 0.9 | 0.7 – 1.1 | 0.159 | 1.0 | 0.8 – 1.3 | 0.884 |
| Neuroblastoma | 1.0 | 0.8 – 1.2 | 0.818 | 1.1 | 0.9 – 1.5 | 0.372 |
| Soft tissue sarcoma | 0.9 | 0.7 – 1.0 | 0.103 | 0.9 | 0.7 – 1.1 | 0.378 |
| Bone cancer | 0.8 | 0.7 – 1.0 | 0.027 | 1.0 | 0.8 – 1.2 | 0.656 |
| Non-Hodgkin lymphoma | 0.9 | 0.7 – 1.1 | 0.224 | 1.0 | 0.8 – 1.3 | 0.830 |
| Hodgkin lymphoma (referent) | 1.0 | 1.0 | ||||
| Gender | ||||||
| Female (referent) | 1.0 | |||||
| Male | 1.1 | 1.0 – 1.2 | 0.159 | |||
| Race/Ethnicity | ||||||
| White, non-Hispanic (referent) | 1.0 | 1.0 | ||||
| Other | 0.9 | 0.8 – 1.0 | 0.027 | 0.9 | 0.8 – 1.0 | 0.041 |
| Health Insurance | ||||||
| No | 1.1 | 0.9 – 1.2 | 0.534 | |||
| Yes or Canadian (referent) | 1.0 | |||||
| Household Income | ||||||
| < $20,000 | 1.0 | 0.9 – 1.1 | 0.836 | |||
| ≥ $20,000 (referent) | 1.0 | |||||
| Education | ||||||
| High school or less | 1.1 | 1.0 – 1.3 | 0.022 | |||
| Post-high school education (referent) | 1.0 | |||||
| Age at Diagnosis (years) | ||||||
| 0–4 | 0.8 | 0.7 – 1.0 | 0.011 | |||
| 5–9 | 0.8 | 0.7 – 0.9 | 0.001 | |||
| 10–14 | 0.8 | 0.7 – 0.9 | 0.006 | |||
| 15–20 (referent) | 1.0 | |||||
| Age at Interview (years) | ||||||
| Per 5-year increase | 1.1 | 1.0 – 1.1 | <0.001 | 1.1 | 1.0 – 1.1 | 0.006 |
| Care at Cancer Center ≤ 2 y ago | ||||||
| No | 1.5 | 1.3 – 1.6 | <0.001 | 1.2 | 1.0 – 1.4 | 0.012 |
| Yes (referent) | 1.0 | |||||
| Cancer Treatment Summary | ||||||
| No | 1.5 | 1.3 – 1.6 | <0.001 | 1.3 | 1.2 – 1.5 | <0.001 |
| Yes (referent) | 1.0 | 1.0 | ||||
| Transfusion History | ||||||
| No transfusion | 2.9 | 2.6 – 3.3 | <0.001 | 2.6 | 2.3 – 3.0 | <0.001 |
| Responded unsure | 2.6 | 2.3 – 3.0 | <0.001 | 2.2 | 1.9 – 2.6 | <0.001 |
| Transfusion for cancer (referent) | 1.0 | 1.0 | ||||
†
Total (N=9168) excludes survivors who had a transfusion after 1993 for a non-cancer cause (n=74); “No prior testing” includes survivors who were uncertain about prior testing
*
Models do not include “physician discussed HCV ≤ 2 y ago” because the strong association with “no prior testing” outcome may mask other associations