Table 1.

Baseline characteristics of the study population (Mean values and standard deviations)

	Placebo			EGCG
	n	Mean	SD	n	Mean	SD
Age (years)	42	50·57	6·48	46	52·15	6·43
Insulin sensitivity
Fasting insulin (mU/l)	42	10·74	4·52	46	11·06	4·95
HOMAIR	42	2·56	1·17	46	2·66	1·25
OGTTISI	33	69·76	32·02	37	63·47	30·45
Insulin secretion
HOMA%B	42	122·07	51·60	46	123·11	54·41
OGTTInsulinogenic index	38	21·50	12·62	42	26·03	33·19
Glucose tolerance
Fasting glucose (mmol/l)	42	5·31	0·43	46	5·37	0·51
OGTT2 h glucose (mmol/l)	41	5·78	1·49	46	5·94	1·68
OGTTTotalAUCglucose (mmol h/l)	33	14·59	3·20	37	15·46	3·01
HbA1c (%)	42	5·12	0·32	45	5·28*	0·43
Metabolic risk factors
BMI (kg/m2)	42	30·96	2·45	46	31·21	2·80
Waist circumference (cm)	42	106·14	7·34	46	107·04	8·85
Body fat (%)	41	28·21	2·81	46	29·52	3·98
Systolic blood pressure (mmHg)	42	138·15	18·23	46	136·16	13·00
Diastolic blood pressure (mmHg)	42	87·17	9·22	46	86·67	7·26
Total cholesterol (mmol/l)	42	5·39	1·06	46	5·64	1·09
HDL-cholesterol (mmol/l)	42	1·17	0·20	46	1·20	0·24
LDL-cholesterol (mmol/l)	42	3·51	0·86	46	3·65	1·03
TAG (mmol/l)	42	1·75	0·94	46	1·69	0·81
Diet and physical activity
Alcohol (g/d)	42	21·08	18·01	45	24·49	23·32
Carbohydrate (g/d)	42	268·26	68·57	45	262·36	65·29
Fat (g/d)	42	103·13	24·89	45	92·00*	24·87
Protein (g/d)	42	98·43	20·26	45	94·37	18·62
Total estimated energy	42			45
kJ/d		10 338·29	2076·94		9852·65	1767·87
kcal/d		2470·91	496·40		2354·84	422·53
Average Wake Movement (counts/min)	34	291·36	97·79	41	318·42	79·32

AUC, area under the curve; EGCG, epigallocatechin-3-gallate; HOMA_IR, homeostasis model assessment of insulin resistance; HOMA_%B, homeostasis model assessment of pancreatic β-cell function; OGTT, oral glucose tolerance test.

Mean values were significantly different from those of the placebo:

^*P≤0·05.