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. Author manuscript; available in PMC: 2010 Feb 10.
Published in final edited form as: J Biol Chem. 2006 Dec 18;282(8):5560. doi: 10.1074/jbc.M603669200

FIGURE 6. Caspase proteolysis of integrin β4 promotes apoptosis.

FIGURE 6

JEB pools stably expressing GFP vector or GFP-tagged WT-β4, D1109E-β4, or Tr-β4 were treated with 5 μg/ml TRAIL for the indicated times, and apoptotic nuclei were scored as described under “Experimental Procedures.” Data are presented as the mean ± S.E. of three experiments (left panel). *, p < 0.05 versus D1109E; ***, p < 0.001 versus D1109E. The expression of each construct in JEB pools before TRAIL treatment was determined by immunoblotting using a GFP antibody (right panel).