TABLE 3.
Linear regression models for each dependent variable entering DXA leg fat mass (FM) alone (model 1) and after adjustment for trunk FM (model 2), CT abdominal visceral fat volume (VFV, model 3), or sc fat volume (SFV, model 4)
| Dependent variable | Independent variables | Model 1 | Model 2 | Model 3 | Model 4 |
|---|---|---|---|---|---|
| INS0 | Leg FM | 0.34 ± 0.17 (0.05) | −0.56 ± 0.19 (<0.01) | −0.07 ± 0.16 (0.68) | −0.22 ± 0.24 (0.37) |
| Trunk FM | 1.42 ± 0.21 (<0.001) | ||||
| VFV | 0.73 ± 0.11 (<0.001) | ||||
| SFV | 0.77 ± 0.24 (<0.01) | ||||
| R2 | 0.04 | 0.36 | 0.34 | 0.14 | |
| INSAUC | Leg FM | 0.16 ± 0.15 (0.30) | −0.49 ± 0.19 (<0.05) | −0.11 ± 0.15 (0.48) | −0.19 ± 0.22 (0.40) |
| Trunk FM | 1.02 ± 0.20 (<0.001) | ||||
| VFV | 0.48 ± 0.11 (<0.001) | ||||
| SFV | 0.48 ± 0.22 (<0.05) | ||||
| R2 | 0.01 | 0.23 | 0.18 | 0.06 | |
| INSAUC × GLUAUC | Leg FM | −0.02 ± 0.15 (0.89) | −0.68 ± 0.22 (<0.01) | −0.19 ± 0.18 (0.31) | −0.25 ± 0.27 (0.36) |
| Trunk FM | 1.37 ± 0.24 (<0.001) | ||||
| VFV | 0.66 ± 0.13 (<0.001) | ||||
| SFV | 0.59 ± 0.27 (<0.05) | ||||
| R2 | 0.01 | 0.27 | 0.22 | 0.06 | |
| TG | Leg FM | −0.052 ± 0.15 (0.89) | −0.39 ± 0.15 (<0.05) | −0.33 ± 0.14 (<0.05) | −0.32 ± 0.21 (0.13) |
| Trunk FM | 0.51 ± 0.10 (<0.001) | ||||
| VFV | 0.55 ± 0.10 (<0.001) | ||||
| SFV | 0.41 ± 0.21 (0.05) | ||||
| R2 | 0.00 | 0.21 | 0.24 | 0.04 | |
| HDL | Leg FM | −0.10 ± 0.09 (0.26) | 0.21 ± 0.11 (0.06) | 0.06 ± 0.09 (0.52) | 0.13 ± 0.12 (0.30) |
| Trunk FM | −0.48 ± 0.12 (<0.001) | ||||
| VFV | −0.27 ± 0.06 (<0.001) | ||||
| SFV | −0.31 ± 0.12 (0.12) | ||||
| R2 | 0.14 | 0.17 | 0.19 | 0.08 |
Data represent β̂ ± SE β̂ (P value). HDL, High-density lipoprotein cholesterol. Contributions of the dependent variables that remained significant after adjustment are in bold type.