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. Author manuscript; available in PMC: 2010 Feb 10.
Published in final edited form as: J Neurochem. 2007 Jan 4;101(1):87. doi: 10.1111/j.1471-4159.2006.04346.x

Fig. 1.

Fig. 1

CB2, but not CB1, receptor mRNA is dramatically and selectively up-regulated in the spinal cords of G93A mice in a temporal pattern closely paralleling disease progression. (a) Comparison of CB2 (left panel) and CB1 (right panel) mRNA expression in spinal cords of G93A mice at various ages, relative to age-matched WT-OE control mice. (inset) Separation of PCR products by 1% agarose gel electrophoresis. (b) Comparison of CB2 (left panel) and CB1 (right panel) mRNA expression in various brain regions of 120-day-old G93A mice, relative to age-matched WT-OE control mice. (c) Comparison of CB2 (left panel) and CB1 (right panel) mRNA expression in cervical and lumbar regions of spinal cords of 120-day-old G93A mice, relative to age-matched WT-OE control mice. *, **Significantly different from mRNA expression in WT-OE control mice, p < 0.05, 0.01 (non-paired Student’s t-test). a–cFold-changes that are designated with different letters are significantly different, p < 0.05 (anova followed by a Dunnett’s post hoc comparison).