Table 2.
mRNA half-life (t1/2).
| Cancer tissue | Cell line | Long mRNA t1/2 (h)* | Short mRNA t1/2 (h)* | Short/long |
|---|---|---|---|---|
| IMP-1 | ||||
| Lung | 4.2 ± 1.4 | 9.0 ± 2.5 | 2.1 | |
| Colon | SW480 | 6.2 ± 0.4 | 12.3 ± 4.3 | 2.0 |
| Breast | HBL100 | 2.3 ± 0.9 | 6.4 ± 1.0 | 2.8 |
| Breast | MDA-MB231 | 4.1 ± 0.5 | 6.7 ± 4.0 | 1.6 |
| Breast | MDA-MB361 | 1.8 ± 0.3 | 4.5 ± 1.6 | 2.5 |
| Cyclin D1 | ||||
| Breast | MCF-7 | 1.9 ± 0.2 | 3.8 ± 0.7 | 2.0 |
| Breast | MDA-MB361 | 8.0 ± 0.1 | 22.4 ± 6.3 | 2.8 |
| Breast | MDA-MB453 | 1.5 ± 0.5 | 6.3 ± 2.7 | 4.2 |
| Cyclin D2 | ||||
| Sarcoma | U2OS | 2.3 ± 0.2 | 3.5 ± 1.1 | 1.5 |
| Colon | SW480 | 3.1 ± 0.9 | 20.6 ± 12.4 | 6.6 |
| Colon | LoVo | 13.8 ± 1.4 | 9.3 ± 1.8 | 0.7 |
*
Reported is the mean ± standard deviation.