CBD has no clear effects on seizure latency in vivo. Bar graphs showing lack
of effects of CBD (1, 10, and 100 mg/kg) on latency to the first sign of a
seizure (A), latency to clonic seizures (B), and latency to tonic-clonic
seizures (C). Each data set n = 15 animals. Note that CBD
(1 mg/kg) reduced latency to tonic-clonic seizures; this proconvulsant
action was not observed at higher CBD doses. **, P
≤ 0.01 (one-way analysis of variance) with a post hoc Tukey
test).