Table 1. MCPyV DNA in biopsies of immunocompetent patients without MCC*.
| Histologic diagnosis | No. samples | No. (%) MCPyV-positive by nested PCR |
|---|---|---|
| Papilloma/wart | 4 | 0 (0) |
| Actinic keratosis | 7 | 0 (0) |
| Keratoacanthoma | 7 | 3 (43) |
| Squamous cell carcinoma | 6 | 1 (17) |
| Bowen disease/carcinoma | 4 | 1 (25) |
| Basal cell carcinoma | 21 | 3 (14) |
| Malignant melanoma | 12 | 2 (17) |
| All skin tumors | 61 | 10 (16) |
| Perilesional healthy skin | 34 | 8 (24) |
*MCPyV, Merkel cell polyomavirus; MCC, Merkel cell carcinoma. All samples shown were negative for Merkel cell polyomavirus in single-round PCR. Six MCPyV-positive perilesional samples had an MCPyV-positive lesional counterpart (3 basal cell carcinomas, 2 keratoacanthomas, 1 squamous cell carcinoma); 1 MCPyV-positive perilesional biopsy had a MCPyV-negative counterpart (basal cell carcinoma); and of 1 MCPyV-positive perilesional biopsy the lesional counterpart was not available. For origin of samples see (7).