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. Author manuscript; available in PMC: 2011 Feb 3.
Published in final edited form as: Cell Metab. 2010 Feb 3;11(2):136. doi: 10.1016/j.cmet.2009.12.009

Figure 1. Bone Mass is Decreased Following FoxOs Deletion.

Figure 1

(A-D) 12 wk-old female and male mice were injected with pI-pC and sacrificed 5 wk later.

(A) mRNA levels of FoxOs in calvaria (calv), vertebra (vert), liver or spleen from male mice determined by qRT-PCR (n=8 mice/group).

(B) BMDs determined by DEXA 1 d before and 5 wk following pI-pC injections (n=10-17 mice/group). *p<0.05 vs respective Mx-Cre- by Student's t-test

(C) Cortical width measured by micro-CT in femurs (n=10-17 mice/group). *p<0.05 vs respective Mx-Cre- by Student's t-test

(D) Histomorphometric analysis of longitudinal undecalcified sections of L1-L3 vertebrae of male mice (n=6-7 mice/group). BA/TA=bone area per tissue area; Tb=trabecular.

*p<0.05 by Student's t-test.