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. 2009 Dec 23;35(4):1016–1025. doi: 10.1038/npp.2009.207

Figure 4.

Figure 4

VPA assessment in the water maze. Memory-impaired aged rats that received chronic treatment with VPA or saline performed at a comparable level at the end of the water maze training phase (Trial 6), but those treated with VPA at 100 mg/kg/day (VPA 100) showed less forgetting as measured by path length (a) and escape latency (b) after a 6-h delay (Retention Trial) compared with their counterparts treated with saline (VEH) or VPA at 50 mg/kg/day (VPA 50). See text for details of data analysis.