Table 4.

Timing of Events for Patients Achieving a CR

Protocol		85-01	87-01	91-01	95-01
Patients achieving CR		217	356	370	480
Events 0–5 years in CCR		44 (20%)	72 (20%)	55 (15%)	77 (16%)
Relapse		36	65	43	73
SMN		1	2	0	1
Remission Death		7	5	12	3
Events 5–10 years in CCR		1 (0.5%)	9 (2.5%)	9 (2.4%)	7 (1.5%)
Relapse		1	7	8	6
SMN		0	1	1	1
Remission Death		0	1	0	0
Events ≥10 years in CCR		1 (0.5%)	1 (0.3%)	2 (0.5%)	1 (0.2%)
Relapse		0	0	2	0
SMN		0	0	0	1
Remission Death		1	1	0	0
# Free from Adverse Events		171 (79%)	274 (77%)	304 (82%)	395 (82%)
# Alive		178	306	324	438