Fig 5. fbnA2A KO mice are protected against MPTP-induced loss of dopaminergic cells in the SNc.
(A) shows representative sections from SNc immunostained for TH. Inserts show higher magnification of TH-labelled (left) and cresyl violet-labelled (right) cells. Mice were treated with MPTP (20 mg/kg once a day for 4 days)or vehicle. (B) shows analysis of TH immunostaining in fbnA2AKO mice, reported as a percentage of TH-positive cells as compared to vehicle-treated mice. Tukey’s post hoc test: * p<0.05 versus vehicle group; # p<0.05 versus WT MPTP group. Scale bar: 50 μm.