Alignment of the GRXCR1 Proteins of Different Species
(A) Overview of the conserved domains in GRXCR1 as predicted by different software tools. The GRX-like domain is predicted to be present by all three programs. However, the exact positions differ.
(B) An alignment of GRXCR1 orthologs was made with ClustalW and Jalview,39,40 and part of the GRXCR1 protein is shown. Abbreviations are as follows: Hs, Homo sapiens; Pt, Pan troglodytes; Mm, Mus musculus; Rn, Rattus norvegicus; Gg, Gallus gallus; Dr, Danio rerio. Fully conserved amino acids are marked in dark gray, and less-conserved amino acids are in lighter colors. Accession numbers of the various protein sequences are as follows: Hs GRXCR1, NP_001073945.1; Pt LOC461192, XP_517170.2; Mm Grxcr1, NP_001018019.1; Rn Grxcr1, XP_573590.2; Gg LOC770624, XP_001233963.1; Dr LOC100150769, XP_001919567.1.