Table 2.
Colonization characteristics
| Variable | Period | p-value* | ||
|---|---|---|---|---|
| Baseline | Heterogeneous | Homogeneous | ||
| Cephalosporin-resistant Enterobacteriaceae | ||||
| Patients with CRE colonization (%) | 83a (18.2) | 26 (14.8) | 29 (21.5) | 0.31/0.39 |
| Patients with colonization on admission (%) | 33 (7.2) | 11 (6.3) | 12 (8.9) | 0.65/0.53 |
| Patients with acquired colonization (%) | 44 (9.6) | 14 (8.0) | 16 (11.9) | 0.50/0.45 |
| Acquisition rate/1,000 patient days at risk | 14 | 14 | 18 | 0.95/0.69 |
| Mean days to acquisition | 7 ± 9 | 6 ± 7 | 7 ± 8 | 0.71/0.73 |
| Ciprofloxacin-resistant CRE | ||||
| Patients with ciprofloxacin-resistant CRE | 16 (3.5) | 4 (2.3) | 11 (8.1) | 0.43/0.02 |
| Patients with ciprofloxacin-resistant CRE isolate on admission | 9 (2.0) | 1 (0.6) | 1 (0.8) | 0.30/0.47 |
| Patients with acquired ciprofloxacin-resistant CRE isolate | 6 (1.3) | 3 (1.7) | 8 (6.0) | 0.71/< 0.01 |
| Mean days to acquisition | 7 ± 10 | 7 ± 8 | 7 ± 8 | 0.98/0.47 |
| Acquisition rate ciprofloxacin-resistant isolate/1,000 patient days | 2.1 | 2.5 | 8.3 | 0.50/0.01 |
Origin of colonization (i.e., present on admission or acquired) could not be determined for six patients, because cultures were either taken more than 48 h after admission or patients had been admitted before the start of the study period
aThis includes four patients present in the unit at the time of study onset
* Comparison of baseline versus heterogeneous/homogeneous