Table 3.
Imprinting analysis of rs941576 A>G
Region | N | exp(-θ̂) | 95% CI | p |
---|---|---|---|---|
UK | 361 | 0.792 | 0.724 – 0.866 | 9.40 × 10−3 |
Asia-Pacific | 32 | 0.88 | 0.656 – 1.18 | 0.662 |
Other Europe | 257 | 0.725 | 0.644 – 0.815 | 6.08 × 10−3 |
USA | 184 | 0.764 | 0.676 – 0.863 | 0.028 |
Finland | 397 | 0.697 | 0.632 – 0.769 | 2.25 × 10−4 |
Overall | 1231 | 0.749 | 0.712 – 0.789 | 1.85 × 10−8 |
Imprinting analysis using family data divided by broad geographical region. N is the number of informative families (which is less than the total number of families available, as only transmissions from asymmetric parents are informative). exp(-θ̂) is the ratio of the allelic effect for a paternally inherited risk allele compared to a maternally inherited allele.