Table 1.
Patient characteristics
Variables | |
---|---|
Age, mean (s.d.), years | 61 (10) |
Aged >61 years, n (%) | 63 (46) |
Race (Caucasian), n (%) | 127 (93) |
BMI, median (IQR), kg/m2 | 26 (23–30) |
DMARDs (yes), n (%) | 118 (86) |
Smoking, median (IQR), pack-years | 1 (0–17) |
High glucocorticoid usea, n (%) | 41 (30) |
No history of glucocorticoid use, n (%) | 41 (30) |
Current osteoporosis medication use, n (%) | 19 (14) |
Disease duration, median (IQR), years | 13 (7–23) |
Early RAb, n (%) | 26 (19) |
Seropositive (RF and/or anti-CCP), n (%) | 105 (76) |
RF status positive, n (%) | 88 (64) |
Anti-CCP positive, n (%) | 87 (63) |
MDHAQ score, median (IQR) | 0.6 (0.2–1.0) |
DAS28, median (IQR) | 3.7 (2.5–4.9) |
Time difference, median (IQR), monthsc | 7 (1–14) |
Hand DXR-BMD, mean (s.d.), g/cm2 | 0.52 (0.09) |
Total hip DXA, mean (s.d.), g/cm2 | 0.85 (0.11) |
Lumbar spine DXA, mean (s.d.), g/cm2 | 0.97 (0.16) |
Lumbar spine BMD analysis consisted of 129 patients; total hip BMD analysis consisted of 99 patients. IQR is given between 25th and 75th percentiles. aHigh glucocorticoid use is defined as a cumulative lifetime exposure of >5 g. bEarly RA defined as disease duration ⩽5 years. cVariable created to account for time difference (in months) between date of hand X-ray for hand DXR measurement and date of total hip or lumbar spine DXA for BMD measurement.