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. Author manuscript; available in PMC: 2010 Feb 11.
Published in final edited form as: Neurocrit Care. 2009 Jan 4;11(1):14. doi: 10.1007/s12028-008-9179-3

Table 2.

Natremic response by 12 h for all doses (divided by groups)

Group 1 n = 20 Group 2 n = 25 Group 3 n = 19
Baseline Na+ 131.4 ± 3.0 131.4 ± 3.0 132.8 ± 5.1
Peak Na+ (within 12 h) 137.1 ± 2.8† 136.7 ± 2.7† 135.5 ± 4.3†
Peak change in Na+ 6.31 ± 3.0 5.76 ± 3.2 2.33 ± 2.8
Increase by ≥4 mEq/l 12/16 (75%) 15/21 (71%) 8/18 (44%)
Increase by ≥6 mEq/l 9/16 (56%) 11/21 (52%) 2/18 (11%)‡
Na+ correct >135 12/16 (75%) 15/21 (71%) 8/18 (44%)

Na+ = serum sodium (mEq/l)

†

P < 0.0001 compared to baseline Na+ (paired t-test);

P = 0.001 compared to group 2 (ANOVA);

‡

P < 0.01 compared to group 2 (chi-squared)