Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Natremic response for doses in group 1 out to 72 h
| Endpoint | Results |
|---|---|
| Peak Na+ | 139.40 ± 4.82† |
| Peak change in Na+ | 8.0 ± 4.1 |
| Change in Na+ at 72 h | 5.12 ± 4.0† |
| Increase by ≥4 mEq/l | 19/20 (95%) |
| Increase by ≥6 mEq/l | 14/20 (70%) |
| Na+ correct >135 | 18/20 (90%) |
| Sustained rise ≥4 at 72 h | 11/16 (69%) |
Na+ = serum sodium (mEq/l)
P < 0.0001 compared to baseline Na+ (paired t-test)
