Table 3.
Impact of a single hemodialysis session on ADMA and SDMA levels
| Subjects |
Dialysis filter DM/TT |
ADMA pre, μM |
ADMA post, μM |
% reduction ADMA |
SDMA pre, μM |
SDMA post, μM |
% reduction SDMA |
|
|---|---|---|---|---|---|---|---|---|
| Vallance (1992) |
3 |
n.i. |
4.0 |
2.1 |
>40% |
n.i. |
n.i. |
n.i. |
| Arese (1995) | 5 | CU/PS | ∼1.35∗ | ∼0.52∗ | ∼61%∗ | ∼2.93∗ | ∼1.25∗ | ∼57%∗ |
| PFD/HD/HDF/4 h |
||||||||
| MacAllister (1996) | 6 | PS | 0.99 | 0.77 | ∼22% | 3.78 | 2.23 | ∼41% |
| HD/4 h |
||||||||
| Anderstam (1997) | 12 | n.i. | ∼0.59∗ | ∼0.45∗ | ∼23% | ∼2.85∗ | ∼1.71∗ | ∼40% |
| HD/n.i. |
||||||||
| Kielstein (1999) | 8 | HP | ∼5.0∗ | ∼6.0∗ | 0% | 3.97 | 6.25 | 0% |
| HD/4.5 h |
∼50% 5 h post HD∗ vs. pre-dialysis |
0% 5 h post HD vs. pre-dialysis |
||||||
| Schmidt (1999) | 11 | n.i. | 4.14 | 1.45 | ∼65% | 1.41 | 0.62 | ∼56% |
| HD/3.5–4 h |
||||||||
| Kang (1999) | 10 | PS | 8.0 | 5.0 | ∼37% | n.i. | n.i. | n.i. |
| HD/4 h |
||||||||
| Gomez-Fernandez (2000) | 6 | CU/PAN/SPAN | 5.8 CU | 0.9 CU | ∼84% CU | n.i. | n.i. | n.i. |
| HD/4 h | 5.0 PAN | 2.4 PAN | ∼52% PAN | |||||
| 4.9 SPAN |
1.5 SPAN |
∼69% SPAN |
||||||
| Wahbi (2001) | 17 | n.i. | 0.99 | 0.63 | ∼36% | 4.53 | 2.95 | ∼35% |
| HD/n.i. |
||||||||
| Cross (2001) | 16 | HP | 0.68 | 0.43 | ∼37% | n.i. | n.i. | n.i. |
| HD/4 h |
||||||||
| Schroder (2001) | 6 | CE/PA | n.i. | n.i. | ∼40–65%∗ | n.i. | n.i. | ∼50–70%∗ |
| HD/HDF/5 h |
||||||||
| Raj (2002) | 27 | PS | 4.0 | 1.6 | ∼60% | n.i. | n.i. | n.i. |
| HD/4 h |
||||||||
| Kielstein (2004) | 30 | PS | 4.35 | 4.76 | 0% | n.i. | n.i. | n.i. |
| Genius-HD/∼4 h |
||||||||
| Bergamini (2004) | 11 | PS | 3.62 | 2.31 | ∼36% | 6.30 | 3.61 | ∼43% |
| HD/4 h |
||||||||
| Mochizuki (2005) | 10 | PS | 2.2 | 2.4 | 0% | n.i. | n.i. | n.i. |
| HD/4 h |
45% 4 h post HD |
|||||||
| Morimoto (2005) | 10 | PS/PSE | 0.69 PS | 0.41 PS | ∼41% PS | n.i. | n.i. | n.i. |
| HD/4 h |
0.74 PSE |
0.41 PSE |
∼45% PSE |
|||||
| Kalousova (2006) | 20 | PS | 0.81 HD | 0.52 HD | ∼36% HD | ∼3.2 HD∗ | ∼1.8 HD∗ | 44% HD |
| HD/HDF/4 h |
0.79 HDF |
0.48 HDF |
∼39% HDF |
∼3.1 HDF∗ |
∼1.6 HDF∗ |
48% HDF |
||
| Soveri (2007) | 22 | n.i. | 0.99 | 0.73 | ∼26% | n.i. | n.i. | n.i. |
| HD or HDF/4 h |
||||||||
| Grooteman (2007) | 15 | CU/PS/PES | 0.62 | 0.43 | ∼32% | 2.55 | 1.42 | ∼44% |
| HD/4–5 h | no differences in dialyzer clearance | no differences in dialyzer clearance |
DM = Dialysis mode; TT = treatment time; CE = cellulose; CU = cuprophane; HP = hemophane; PS = polysulphone; PSE = vitamin E-coated poly-sulphone; PES = polyethersulfone; PA = polyamide; PAN = polyacrylnitrile; SPAN = special polyacrylnitrile; HD = bicarbonate hemodialysis; HDF = hemodiafiltration; PFD = paired filtration dialysis. An asterisk indicates the estimated mean.