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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Clin Infect Dis. 2010 Mar 1;50(S2):S54. doi: 10.1086/648966

Figure 2.

Figure 2

Release of TNF-α after incubation of human PBMCs for 4 hours with OMV vaccines. The OMV concentrations that resulted in a 10-fold increased release of TNF-α concentrations above background are shown on the X intercepts. White circles, native OMV from wildtype strain; gray squares, OMV vaccine prepared from LpxL1 KO mutants; black triangles, detergent-extracted OMV vaccines from corresponding wildtype strains. Adapted from published data [65] with permission from American Society for Microbiology.