Table 6.
Multiple logistic regression analysis showing predictors for final outcome of infantile spasms in terms of resolution of seizures
| Variables | Resolution of Seizures Adjusted OR * |
(EEG and/or clinical) 95% CI ** |
|---|---|---|
| Type of therapy (p < 0.001) | ||
| Receipt of second drug | 1 | - |
| ACTH monotherapy | 4.2 | 0.6 - 6.8 |
| Vigabatrin monotherapy | 4.6 | 1.1 - 7.2 |
| Etiology (p < 0.001) | ||
| Symptomatic | 1 | - |
| Cryptogenic | 1.2 | 0.4 - 2.1 |
| Idiopathic | 4.4 | 1.6 - 6.9 |
| Age at Diagnosis (p = 0.04) | ||
| > 12 months | 1 | - |
| 6 - 12 months | 1.2 | 0.8 - 1.5 |
| < 6 months | 1.3 | 0.6 - 2.1 |
* OR = Odds Ratio
** CI = Confidence Interval