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. Author manuscript; available in PMC: 2010 Feb 12.
Published in final edited form as: Pharm Res. 2008 Dec 13;26(4):836–845. doi: 10.1007/s11095-008-9782-1

Figure 1.

Figure 1

Scheme of the Dox-CPP cell delivery complexes. (A) Amino acid sequences of the CPPs used for conjugation (single letter code). The extra cysteine used for chemical conjugation of Dox is indicated in blue. Mutated cysteine residues of MCa, replaced by Abu residues, are in bold. (B) Chemical structure of Dox (red) and SMCC crosslinker (black) bound to Cys-CPP (blue). Synthesis of peptides and coupling method with Dox are described in Materials and Methods. Resulting conjugates are indicated in the far right.