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. 2010 Feb 12;6(2):e1000842. doi: 10.1371/journal.pgen.1000842

Table 1. Top 4 SNPs associated with diabetic nephropathy in a genome-wide screening.

	Nephropathy^(a)	p for HWE^(b)	Control^(a)	p for HWE^(b)	Smallest p (model)
rs2268388 (C > T)	0.25 (413/276/48)	0.83	0.17 (379/155/18)	0.66	1.4×10⁻⁶ (allelic)
Ch 12, ACACB
rs2250736 (C > T)	0.278 (394/288/63)	0.32	0.338 (233/262/55)	0.13	0.0002 (dominant)
Ch 3, CACNA1D
rs3777587 (G > A)	0.523 (156/399/191)	0.05	0.459 (166/269/120)	0.57	0.0002 (dominant)
Ch 6, CLIC5
rs7148607 (T > C)	0.34 (318/353/76)	0.06	0.39 (219/243/94)	0.13	0.0003 (recessive)
Ch 14

^(a)minor allele frequencies are shown, and genotype counts are in parenthesis.

^(b)p values for Hardy Weinberg equilibrium test.