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. 2010 Feb 12;6(2):e1000846. doi: 10.1371/journal.pgen.1000846

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Vaquerizas et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Probability density distributions of distance measurements for mock treated (red) and Nup153-depleted cells (purple). Histograms depict the proportion of nuclei for which the FISH signal is located within the 30% distance threshold (DAPI in blue). (A-C) NAR targets on the male X chromosome (T4, T7, T5) relocalise to the interior upon treatment, indicating that peripheral localisation is dependent on Nup153. (D-F) NAR and non-NAR targets at the interior remain unaffected upon Nup153-depletion.

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