Table 4.

Symptom Distress Scale: Comparisons of Mean Symptom Intensity and Distress at Diagnosis vs. Those at Each Time Point

Item	At diagnosis	Week 12	Week 23	After completion of therapy
SDS Total Scale Score	23.7 (7.0)	17.4 (4.5) ^	17.5 (5.0) ^	15.0 (4.1) ^
How much you are able to get around	3.3 (1.3)	2.7 (1.2)	2.3 (1.1) ^	2.0 (1.0) ^
How tired you are feeling	3.0 (1.3)	2.2 (1.2) ^	2.2 (1.1)	1.7 (0.8) ^
How good your appetite is	2.8 (1.4)	1.6 (1.0) ^	1.7 (1.0) ^	1.3 (0.6) ^
How much pain you are having	1.9 (1.0)	1.1 (0.4) ^	1.2 (0.5) ^	1.3 (0.5) ^
How much nausea you have	1.8 (1.1)	1.4 (0.8)	1.4 (0.7)	1.1 (0.5) ^
How well you slept last night	2.5 (1.3)	1.6 (0.9) ^	1.9 (1.2)	1.8 (1.1)
How you feel about your appearance	2.1 (1.2)	1.8 (0.9)	1.7 (0.9)	1.4 (0.6)
How you are feeling	2.6 (1.0)	2.0 (1.0)	1.9 (0.8) ^	1.7 (0.8) ^
How regular your bowels are working	2.0 (1.3)	1.5 (0.8)	1.8 (1.0)	1.2 (0.5) ^
How well you are able to concentrate	1.7 (1.1)	1.4 (0.6)	1.5 (0.8)	1.5 (0.8)

^*Lower item and total scores indicate better HRQOL. Standard deviations are shown in parentheses.

^{^}Statistically significant after Bonferonni adjustment (P < (0.05)/72 = 0.0007)